By Lee L. Swanstrom, Christy M. Dunst
This quantity offers a accomplished, state of the art review of the key matters particular to the sector of antireflux surgical procedure. It presents remarkable educational aspect relating to functionality of antireflux surgical procedure from major esophageal surgeons around the globe. This quantity represents the single source of its type devoted particularly to the problems detailed to antireflux surgical procedure. it truly is wealthy intimately and valuable illustrations that train surgeons in right process in addition to offering the reasoning in the back of quite a few options. Written through specialists within the box, Antireflux surgical procedure is of significant price to working towards surgeons who practice gastrointestinal surgical procedure, clinical scholars, surgical citizens, and fellows.
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Extra resources for Antireflux Surgery
The role of overdiagnosis and reclassification in the marked increase of esophageal adenocarcinoma incidence. J Natl Cancer Inst. 2005;97:142–6. 43. Chandrasoma PT, Wickramasinghe K, Ma Y, DeMeester TR. Adenocarcinomas of the distal esophagus and “gastric cardia” are predominantly esophageal adenocarcinomas. Am J Surg Pathol. 2007;31:569–75. 44. Rice TW, Blackstone EW, Rusch VW. 7th edition of the AJCC cancer staging manual: esophagus and esophagogastric junction. Ann Surg Oncol. 2010;17:1721–4.
The second positive effect of alkalinizing gastric contents with proton pump inhibitors is that it controls pain. Heartburn is reduced significantly in most patients because suppression of acid removes the most potent stimulator of pain-sensitive nerve endings. Control of heartburn improves the quality of life for most patients with reflux disease. The availability of proton pump inhibitors for treating reflux disease has in fact, dramatically decreased the misery index of reflux disease in the past five decades.
Anti-reflux surgery has been shown to reverse intestinal metaplasia in the columnar lined esophagus in patients with Barrett esophagus. This occurs uncommonly in patients with long segment Barrett esophagus, but was reported in 73 % of patients with intestinal metaplasia limited to a dilated distal esophagus [64, 65]. The most important question is whether anti-reflux surgery can prevent progression of reflux disease and particularly reflux disease complicated by Barrett’s esophagus to adenocarcinoma.
Antireflux Surgery by Lee L. Swanstrom, Christy M. Dunst