By Jose de Leon (auth.), Jose de Leon (eds.)
Emotional, behavioral, and neuropsychiatric stipulations are universal in people with highbrow disabilities (IDs), such a lot particularly epilepsy, aggression, self-injurious behaviors, and bipolar and different temper issues. regardless of the superiority of such difficulties, there's a shortage within the literature of trustworthy info on scientific remedies for people with IDs.
A Practitioner's advisor to Prescribing Antiepileptics and temper Stabilizers for Adults with highbrow Disabilities presents an in depth framework for prescribing for this not easy inhabitants. that includes the main up to date info on components that tell prescribing, the Guide addresses simple concerns and controversies (e.g., the rift among evidence-based and custom-made medication) in treating adults with cognitive deficits. consumers' particular wishes are emphasised in constructing applicable and powerful pharmacological intervention for superior results and caliber of lifestyles. medicinal drugs mentioned within the Guide comprise carbamazepine, clonazepam, diazepam, ethosuximide, felbamate, gabapentin, lacosamide, lamotrigine, levetiracetam, lithium, lorazepam, oxcarbazepine, phenobarbital, phenytoin, pregabalin, primidone, rufinamide, tiagabine, topiramate, valproate, and zonisamide. for every of those compounds, the ideas cover:
- Indications to be used; relative and absolute contraindications.
- Assessment in the course of remedy; healing drug tracking; indications and signs for caretakers.
- Dosage: management; preliminary and greatest prompt dosage; variations linked to drug-drug interactions, own features, and (where applicable) genetic variations.
- Adverse drug reactions: universal, really unusual, and in all probability deadly, plus danger of metabolic syndrome.
- Guidelines for discontinuation.
- References, tables, and drug usage reviews.
A Practitioner's advisor to Prescribing Antiepileptics and temper Stabilizers for Adults with highbrow Disabilities is an fundamental decision-making reference for psychiatrists, neuropsychologists, psychopharmacologists, neurologists, internists, and medical psychologists.
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Additional info for A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities
The procedures contained in this guideline may not fully account for all of the possible risks of treatment in this population because of the limited studies available; thus, there will be a need to periodically update this guideline as new information becomes available. Nevertheless, we believe that this guideline provides a useful resource for clinicians who treat epilepsy, mood disorders, and/or challenging behaviors in adult individuals with intellectual disabilities. A carbamazepine drug utilization review that summarizes this guideline is described.
G. (2007a). Pharmacological interventions for epilepsy in people with intellectual disabilities. The Cochrane Database Systematic Reviews, (3), CD005399. G. (2007b). Non-pharmacological interventions for epilepsy in people with intellectual disabilities. The Cochrane Database Systematic Reviews, (4), CD005502. , & Kerr, M. (2009). A prospective multi-centre open label study of the use of levetiracetam as add-on treatment in patients with epilepsy and intellectual disabilities. Seizure, 4, 279–284.
1997); Buchanan (1995); Crawford et al. (2001a); Ettinger et al. (1998); Gidal et al. (2000); Huber et al. (1998); Sunder et al. (2006). Levetiracetam – Focused on ADRs: Brodtkorb et al. (2004); Carpay et al. (2009); Hurtado et al. (2006); Mula et al. (2004); Simister et al. (2007); Szucs et al. (2008). – Open trials: Beavis et al. (2009); Deb and Kaur Saini (2007); Huber et al. (2004); Kelly et al. (2004); Specchio et al. d Oxcarbazepine – Focused on ADRs: Simister et al. (2007). Phenobarbital (and primidone) – Follow-up after discontinuation: Coulter (1988);e Hanzel et al.
A Practitioner's Guide to Prescribing Antiepileptics and Mood Stabilizers for Adults with Intellectual Disabilities by Jose de Leon (auth.), Jose de Leon (eds.)